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  2. Nephron - Wikipedia

    en.wikipedia.org/wiki/Nephron

    Fig.1) Schematic diagram of the nephron (yellow), relevant circulation (red/blue), and the four methods of altering the filtrate. The nephron is the functional unit of the kidney. [3] This means that each separate nephron is where the main work of the kidney is performed. A nephron is made of two parts:

  3. Collecting duct system - Wikipedia

    en.wikipedia.org/wiki/Collecting_duct_system

    Diagram outlining movement of ions in nephron, with the collecting ducts on the right. The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water. At times of ...

  4. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    Diagram showing a schematic nephron and its blood supply. The basic physiologic mechanisms of handling fluid and electrolytes by the nephron - filtration, secretion, reabsorption, and excretion - are labelled.

  5. Renal physiology - Wikipedia

    en.wikipedia.org/wiki/Renal_physiology

    Much of renal physiology is studied at the level of the nephron, the smallest functional unit of the kidney. Each nephron begins with a filtration component that filters the blood entering the kidney. This filtrate then flows along the length of the nephron, which is a tubular structure lined by a single layer of specialized cells and ...

  6. Kidney - Wikipedia

    en.wikipedia.org/wiki/Kidney

    The nephron is the structural and functional unit of the kidney. Each adult human kidney contains around 1 million nephrons, while a mouse kidney contains only about 12,500 nephrons. The kidneys also carry out functions independent of the nephrons.

  7. Loop of Henle - Wikipedia

    en.wikipedia.org/wiki/Loop_of_Henle

    Named after its discoverer, the German anatomist Friedrich Gustav Jakob Henle, the loop of Henle's main function is to create a concentration gradient in the medulla of the kidney. [ 3 ] By means of a countercurrent multiplier system, which uses electrolyte pumps, the loop of Henle creates an area of high urea concentration deep in the medulla ...

  8. Glomerular filtration rate - Wikipedia

    en.wikipedia.org/wiki/Glomerular_filtration_rate

    Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal (kidney) glomerular capillaries into the Bowman's capsule per unit time. [4] Central to the physiologic maintenance of GFR is the differential basal tone of the afferent (input) and efferent (output) arterioles (see diagram).

  9. Mammalian kidney - Wikipedia

    en.wikipedia.org/wiki/Mammalian_kidney

    Within a single nephron, regenerative abilities differ between its parts. [199] In acute toxic and ischemic injuries, the tubules are able to regenerate and restore the function of the nephron. [196] In particular, the proximal part of the nephron, through which up to two-thirds of the primary urine is absorbed, [200] has the ability to ...