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Parietal cells produce potent hydrochloric acid, which damages cells. Gastric chief cells produce pepsinogen, which is activated by the acid to form pepsin. Pepsin is a protease that can digest and damage stomach cells. To prevent these disastrous effects, mucus and bicarbonate ions (HCO 3 −) are secreted by the foveolar cells.
These cells almost fill the tube and the remaining lumen is continued as a very fine channel. Cells found in the gastric glands include mucous neck cells, chief cells, parietal cells, G cells, and enterochromaffin-like cells (ECLs). The first cells of all of the glands are mucus-secreting foveolar cells that line the gastric pits.
The three components include: A compact epithelial cell lining. Cells in the epithelium of the stomach are bound by tight junctions that repel harsh fluids that may injure the stomach lining. A special mucus covering, derived from mucus secreted by surface epithelial cells and Foveolar cells. This insoluble mucus forms a protective gel-like ...
This structure consists of connective tissue covered by a simple squamous epithelium, called the mesothelium, which reduces frictional forces during digestive movements. The intraperitoneal regions include most of the stomach , first part of the duodenum , all of the small intestine , caecum and appendix , transverse colon , sigmoid colon and ...
Approximately 20,000 protein coding genes are expressed in human cells and 75% of these genes are expressed in at least one of the different parts of the digestive organ system. [ 25 ] [ 26 ] Over 600 of these genes are more specifically expressed in one or more parts of the GI tract and the corresponding proteins have functions related to ...
Diagram of the alkaline mucous layer in the stomach with mucosal defense mechanisms. The gastric mucosa is the mucous membrane layer of the stomach, which contains the gastric pits, to which the gastric glands empty. In humans, it is about one mm thick, and its surface is smooth, soft, and velvety.
The connective tissue of the lamina propria is loose and rich in cells. The cells of the lamina propria are variable and can include fibroblasts, lymphocytes, plasma cells, macrophages, eosinophilic leukocytes, and mast cells. [2] It provides support and nutrition to the epithelium, as well as the means to bind to the underlying tissue.
Date: 10 August 2020: Source: Own work: Author: Mikael Häggström, M.D. Author info - Reusing images - Conflicts of interest: None Mikael Häggström, M.D. Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance).