Search results
Results From The WOW.Com Content Network
Cocaine is a relatively "balanced" inhibitor, although facilitation of dopaminergic neurotransmission is what has been linked to the reinforcing and addictive effects. In addition, cocaine has some serious limitations in terms of its cardiotoxicity [188] due to its local anesthetic activity. Thousands of cocaine users are admitted to emergency ...
Types of retinopathy caused by drug abuse include maculopathy, Saturday night retinopathy, and talc retinopathy. Common symptoms include temporary and permanent vision loss, blurred vision, and night blindness. Substances commonly associated with this condition include poppers, heroin, cocaine, methamphetamine, tobacco, and alcohol. [1]
DRIs may be divisible into two different types with different effects: (1) typical or conventional DRIs like cocaine, WIN-35428 (β-CFT), and methylphenidate that produce potent psychostimulant, euphoric, and reinforcing effects; and (2) atypical DRIs like vanoxerine (GBR-12909), modafinil, benztropine, and bupropion, which do not produce such effects or have greatly reduced such effects.
A single-nucleotide polymorphism (SNP) is a genetic variation in which a genome sequence is altered by a single nucleotide (A, T, C or G).NET proteins with an altered amino acid sequence (more specifically, a missense mutation) could potentially be associated with various diseases that involve abnormally high or low plasma levels of norepinephrine due to altered NET function.
Cocaine alters one's state of consciousness. Cocaine affects the neurotransmitters that nerves use to communicate with each other. Cocaine inhibits the reuptake of norepinephrine, serotonin, dopamine, and other neurotransmitters in the synapse, resulting in an altered state of consciousness or a "high" (Aldridge, D., & Fachner, J. ö. 2005).
Drug overdose deaths involving cocaine and psychostimulants such as methamphetamine have been rising quickly in the United States in recent years, and a new report from the US Centers for Disease ...
Cocaine addiction results from complex molecular changes in the brain following multiple exposures to cocaine. [16] Dynorphins have been shown to be an important part of this process. Although a single exposure to cocaine does not affect brain dynorphin levels, repeated exposures to the drug increases dynorphin concentrations in the striatum ...
WebMD said this is due to several factors: the types of drugs mixed in the pink cocaine; whether alcohol is involved; how much pink cocaine is taken; and how the body reacts to the drugs.