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  2. CinCor Pharma Sinks After Disappointing Data From ...

    www.aol.com/news/cincor-pharma-sinks...

    CinCor Pharma Inc (NASDAQ: CINC) announced topline results and completion of its Phase 2 HALO trial of baxdrostat in patients with uncontrolled hypertension taking up to two blood pressure ...

  3. CinCor (CINC) Tanks Due to Dismal Data on Hypertension Drug

    www.aol.com/news/cincor-cinc-tanks-due-dismal...

    CinCor (CINC) plummets as its phase II study, HALO, evaluating its lead candidate baxdrostat for hypertension, fails to meet its primary endpoint.

  4. Baxdrostat - Wikipedia

    en.wikipedia.org/wiki/Baxdrostat

    Baxdrostat is an investigational drug that is being evaluated for the treatment of hypertension. [1] It is an aldosterone synthase inhibitor. [2] [3] References

  5. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Loop diuretics may also precipitate kidney failure in patients concurrently taking an NSAID and an ACE inhibitor—the so-called "triple whammy" effect. [ 19 ] Because furosemide, torsemide and bumetanide are technically sulfa drugs, there is a theoretical risk that patients sensitive to sulfonamides may be sensitive to these loop diuretics.

  6. Renal physiology - Wikipedia

    en.wikipedia.org/wiki/Renal_physiology

    This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.

  7. Adding stem cells to a kidney transplant could get patients ...

    www.aol.com/news/adding-stem-cells-kidney...

    The three other patients had to go back on the drugs due to either a rejection episode or worsening kidney function. The trial, funded by biotechnology company Medeor Therapeutics, is centered ...

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