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DNA replication occurs during the S-stage of interphase. [13] DNA replication (DNA amplification) can also be performed in vitro (artificially, outside a cell). [14] DNA polymerases isolated from cells and artificial DNA primers can be used to start DNA synthesis at known sequences in a template DNA molecule.
The process of meiosis in females occurs during oogenesis, and differs from the typical meiosis in that it features a long period of meiotic arrest known as the dictyate stage and lacks the assistance of centrosomes. [53] [54] In males, meiosis occurs during spermatogenesis in the seminiferous tubules of the testicles.
Interkinesis or interphase II is a period of rest that cells of some species enter during meiosis between meiosis I and meiosis II. [1] [2] No DNA replication occurs during interkinesis; however, replication does occur during the interphase I stage of meiosis (See meiosis I). During interkinesis, the spindles of the first meiotic division ...
Interphase is the process through which a cell must go before mitosis, meiosis, and cytokinesis. [15] Interphase consists of three main phases: G 1, S, and G 2. G 1 is a time of growth for the cell where specialized cellular functions occur in order to prepare the cell for DNA replication. [16]
The eukaryotic cell cycle consists of four distinct phases: G 1 phase, S phase (synthesis), G 2 phase (collectively known as interphase) and M phase (mitosis and cytokinesis). M phase is itself composed of two tightly coupled processes: mitosis, in which the cell's nucleus divides, and cytokinesis, in which the cell's cytoplasm and cell membrane divides forming two daughter cells.
Figure 1: Schematic of the cell cycle. outer ring: I = Interphase, M = Mitosis; inner ring: M = Mitosis, G 1 = Gap 1, G 2 = Gap 2, S = Synthesis; not in ring: G 0 = Gap 0/Resting. Replication timing refers to the order in which segments of DNA along the length of a chromosome are duplicated.
The stages of interphase are: G 1 (Gap 1), in which the cell grows and functions normally. During this time, a high amount of protein synthesis occurs and the cell grows (to about double its original size) – more organelles are produced and the volume of the cytoplasm increases. If the cell is not to divide again, it will enter G 0. [3]
In eukaryotes, the cell cycle consists of four main stages: G 1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G 2, during which cell growth continues and the cell synthesizes various proteins in preparation for division; and the M phase, during which the duplicated ...