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Subcutaneous injection sites. Commonly used injection sites include: [3]: 723 The outer area of the upper arm. The abdomen, avoiding a 2-inch circle around the navel. The front of the thigh, between 4 inches from the top of the thigh and 4 inches above the knee. The upper back. The upper area of the buttock, just behind the hip bone.
For many biologics (e.g., monoclonal antibodies), injection site reactions are the most common adverse effect of the drug, and have been reported to have an incidence rate of 0.5–40%. [ 2 ] In trials of subcutaneous administration of oligonucleotides , between 22 and 100% of subjects developed reactions depending on the oligonucleotide.
For certain substances, administration via an ID route can result in a faster systemic uptake compared with subcutaneous injections, [1] leading to a stronger immune response to vaccinations, immunology [clarification needed] and novel cancer treatments, and faster drug uptake. [2]
Subcutaneous: Subcutaneous injections are given at a 45-degree angle, usually in the thigh (for babies under the age of 12 months) or upper-outer triceps area for people over 12 months. The MMR ...
Subcutaneous (under the skin). [22] This generally takes the form of subcutaneous injection, e.g. with insulin. Skin popping is a slang term that includes subcutaneous injection, and is usually used in association with recreational drugs. In addition to injection, it is also possible to slowly infuse fluids subcutaneously in the form of ...
Most injector pens are designed for subcutaneous injection just under the skin, but some are designed for injection into muscle. The desired injection site and the skin profile at the injection site will determine what needle length is appropriate for a person to use. [23]
The basilic vein is a large superficial vein of the upper limb that helps drain parts of the hand and forearm. [1] It originates on the medial side of the dorsal venous network of the hand and travels up the base of the forearm, where its course is generally visible through the skin as it travels in the subcutaneous fat and fascia lying superficial to the muscles.
Subcutaneous injection is the preferred delivery method. [3] Belonging to the alpha interferon family of medications, the molecule is PEGylated to prevent breakdown. [3] [4] Approval for medical use in the United States was granted in 2001. [3] It is on the World Health Organization's List of Essential Medicines as a therapy for chronic ...