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Methylphenidate is a stimulant with an addiction liability and dependence liability similar to amphetamine. It has moderate liability among addictive drugs; [102] [103] accordingly, addiction and psychological dependence are possible and likely when methylphenidate is used at high doses as a recreational drug. [103]
In addition, people using methylphenidate also demonstrated improvements in working memory. This is great news, as people with ADHD may have problems with maintaining focus, impulse control, and ...
Clonidine was initially developed as a treatment for high blood pressure. Low doses in evenings and/or afternoons are sometimes used in conjunction with stimulants to help with sleep and because clonidine sometimes helps moderate impulsive and oppositional behavior and may reduce tics. [96] It may be more useful for comorbid Tourette syndrome.
Coingestion of alcohol also increases the blood plasma levels of d-methylphenidate by up to 40%. [46] Liver toxicity from methylphenidate is extremely rare, but limited evidence suggests that intake of β-adrenergic agonists with methylphenidate may increase the risk of liver toxicity. [47]
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. [11] High blood pressure usually does not cause symptoms itself. [ 1 ]
Sympathomimetic drugs are used to treat cardiac arrest and low blood pressure, or even delay premature labor, among other things. These drugs can act through several mechanisms, such as directly activating postsynaptic receptors , blocking breakdown and reuptake of certain neurotransmitters, or stimulating production and release of catecholamines.
Psychosis may also result from withdrawal from stimulants, particularly when psychotic symptoms were present during use. [ 7 ] The most common causative agents are substituted amphetamines , including substituted cathinones , as well as certain dopamine reuptake inhibitors such as cocaine and phenidates .
Many people experience lightheadedness or dizziness at some point in their lifetime, but if you are living with a neurodegenerative condition, like Parkinson’s disease, those symptoms could mean ...
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