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In other words, if you take a dose of 10mg of Lexapro, only 5mg will remain in your bloodstream after 27 to 32 hours.
Escitalopram (at the maximum dose of 20 mg/day) has been found to increase peak levels of the CYP2D6 substrate desipramine by 40% and total exposure by 100%. [8] Likewise, it has been found to increase peak levels of the CYP2D6 substrate metoprolol by 50% and overall exposure by 82%. [8]
Lexapro is an antidepressant that can improve your mood and make symptoms of depression, anxiety, obsessive-compulsive disorder and other mental health issues less severe, helping you to focus on ...
To avoid drug interactions, your healthcare provider will tell you which process to use and how to switch from one antidepressant to another safely based on your medications and overall health.
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50 , meaning "effective dose for 50% of the population".
Paroxetine was the first drug to be FDA-approved for this disorder. Its efficacy is considered beneficial, although not everyone responds favorably to the drug. Sertraline and fluvoxamine extended-release were later approved for it as well, while escitalopram is used off-label with acceptable efficiency.
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