Ads
related to: phenylalanine in human body works- PTEN’s Role In mHSPC
Find Out More Information About The
Impact Of PTEN Deficiency In mHSPC.
- Exploring PTEN Incidence
Learn How PTEN Results Provide Info
On Prostate Cancer Approaches.
- PTEN’s Role In mCSPC
Find Out More Information About The
Impact Of PTEN Deficiency In mCSPC.
- PTEN Biomarker Results
Information On PTEN Deficiency
Status Can Be A Prognostic Tool.
- PTEN’s Role In mHSPC
Search results
Results From The WOW.Com Content Network
Phenylalanine ball and stick model spinning. Phenylalanine (symbol Phe or F) [3] is an essential α-amino acid with the formula C 9 H 11 NO 2.It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine.
This metabolic pathway is nonexistent in the healthy body, but becomes important after peripheral l-DOPA administration in patients with Parkinson's disease or in the rare cases of patients with AADC enzyme deficiency. [11] l-Phenylalanine, l-tyrosine, and l-DOPA are all precursors to the biological pigment melanin.
Phenylalanine hydroxylase (PAH) (EC 1.14.16.1) is an enzyme that catalyzes the hydroxylation of the aromatic side-chain of phenylalanine to generate tyrosine.PAH is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses tetrahydrobiopterin (BH 4, a pteridine cofactor) and a non-heme iron for catalysis.
In mammals it is created from -lactate and L-phenylalanine by the cytosol nonspecific dipeptidase (CNDP2) protein. [1] It is classified as N-acyl-alpha-amino acid and pseudodipeptide. [11] It has also been reported that as an additive, N-L-lactoyl phenylalanine improves the taste of food, conferring an umami flavor [12].
Tyrosine (and its precursor phenylalanine) are precursors of the catecholamine neurotransmitters dopamine, epinephrine and norepinephrine and various trace amines. Phenylalanine is a precursor of phenethylamine and tyrosine in humans. In plants, it is a precursor of various phenylpropanoids, which are important in plant metabolism.
Six amino acids are non-essential (dispensable) in humans, meaning they can be synthesized in sufficient quantities in the body. These six are alanine , aspartic acid , asparagine , glutamic acid , serine , [ 2 ] and selenocysteine (considered the 21st amino acid).
Analogously to phenylalanine hydroxylase and tyrosine hydroxylase, this enzyme uses (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin (BH 4) and dioxygen as cofactors. [ 2 ] In humans, the stimulation of serotonin production by administration of tryptophan has an antidepressant effect [ 3 ] [ 4 ] and inhibition of tryptophan hydroxylase (e.g. by p ...
QDPR (quinoid dihydropteridine reductase) is a human gene that produces the enzyme quinoid dihydropteridine reductase. This enzyme is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4. Tetrahydrobiopterin works with an enzyme called phenylalanine hydroxylase to process a substance called phenylalanine.