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Russell bodies are inclusion bodies usually found in atypical plasma cells that become known as Mott cells. [1] Russell bodies are eosinophilic, homogeneous immunoglobulin (Ig)-containing inclusions usually found in cells undergoing excessive synthesis of Ig; the Russell body is characteristic of the distended endoplasmic reticulum. Russell ...
Inclusion bodies have a non-unit (single) lipid membrane [citation needed].Protein inclusion bodies are classically thought to contain misfolded protein.However, this has been contested, as green fluorescent protein will sometimes fluoresce in inclusion bodies, which indicates some resemblance of the native structure and researchers have recovered folded protein from inclusion bodies.
Inclusion bodies that when present aid in the diagnosis of conditions of or affecting the human integumentary system Name Composition Location Condition(s) Asteroid: Sporotrichosis: Cowdry A: Herpes simplex: Cowdry B: Polio virus: Donovan: Granuloma inguinale: Dutcher: Intranuclear: Primary cutaneous marginal zone lymphoma Multiple myeloma ...
According to Kukushkin, the memories stored in non-brain cells in other parts of the body are memories strictly related to the roles that those specific cells play in human health. Thus, he detailed:
Bizarre cells, which are multinucleated; Mott cells, containing multiple clustered cytoplasmic droplets or other inclusions (sometimes confused with Auer rods, commonly seen in myeloid blasts) Flame cells, having a fiery red cytoplasm [71] [72] Historically, the CD138 has been used to isolate myeloma cells for diagnostic purposes.
Plasma cells with Dutcher and Russell bodies (H&E stain, 100×, oil) Plasma cells are large lymphocytes with abundant cytoplasm and a characteristic appearance on light microscopy. They have basophilic cytoplasm and an eccentric nucleus with heterochromatin in a characteristic cartwheel or clock face arrangement.
Reactive lymphocyte surrounded by red blood cells. In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8 +) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape.
Russell and Lisa Feldman Barrett describe their modified circumplex model as representative of core affect, or the most elementary feelings that are not necessarily directed toward anything. Different prototypical emotional episodes, or clear emotions that are evoked or directed by specific objects, can be plotted on the circumplex, according ...