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Necrotizing fasciitis (NF), also known as flesh-eating disease, is an infection that kills the body's soft tissue. [3] It is a serious disease that begins and spreads quickly. [ 3 ] Symptoms include red or purple or black skin, swelling, severe pain, fever , and vomiting. [ 3 ]
Fasciitis is an inflammation of the fascia, [1] which is the connective tissue surrounding muscles, blood vessels and nerves. In particular, it often involves one of the following diseases: Necrotizing fasciitis
Eosinophilic fasciitis (/ ˌ iː ə ˌ s ɪ n ə ˈ f ɪ l ɪ k ˌ f æ ʃ i ˈ aɪ t ɪ s, ˌ iː oʊ-,-ˌ f æ s i-/ [2] [3]), also known as Shulman's syndrome, [4] is an inflammatory disease that affects the fascia, other connective tissues, surrounding muscles, blood vessels and nerves.
The route of administration of an antibiotic varies. Antibiotics effective against MRSA can be given by IV, oral, or a combination of both, and depend on the specific circumstances and patient characteristics. [4] The use of concurrent treatment with vancomycin or other beta-lactam agents may have a synergistic effect. [21]: 637
Streptococcus dysgalactiae is a gram positive, beta-haemolytic, coccal bacterium belonging to the family Streptococcaceae.It is capable of infecting both humans and animals, but is most frequently encountered as a commensal of the alimentary tract, genital tract, or less commonly, as a part of the skin flora.
Fournier gangrene is a type of necrotizing fasciitis or gangrene affecting the external genitalia or perineum. It commonly occurs in older men, but it can also occur both in women and children and in people with diabetes or alcoholism or those who are immunocompromised.
The 2023 updated Johnson & Johnson Consumer Inc. label for their product discloses three different antibiotics: bacitracin zinc 400 units, neomycin sulfate 3.5 mg, and polymyxin B sulfate 5,000 units, in a relatively low-molecular-weight base of petroleum jelly, cottonseed oil, olive oil, and cocoa butter, and with sodium pyruvate and ...
The development of necrotizing myopathy after statin exposure is insufficient to make the diagnosis. Testing must first exclude other causes of myositis and necrotizing myopathy. [7] A muscle biopsy consistent with SAAM will demonstrate muscle cell death with muscle fiber regeneration and typically has few inflammatory cells.