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Dog appeasing pheromone is secreted by lactating dogs. Dog appeasing pheromone (DAP), sometimes known as apasine, is a mixture of esters of fatty acids released by the sebaceous glands in the inter-mammary sulcus of lactating female dogs. It is secreted from between three and four days after parturition and two to five days after weaning. [1]
Acceptable daily intake or ADI is a measure of the amount of a specific substance (originally applied for a food additive, later also for a residue of a veterinary drug or pesticide) in food or drinking water that can be ingested (orally) daily over a lifetime without an appreciable health risk. [1]
dose area product (DAP) measured in gray centimeters 2; dose length product (DLP) measured in gray centimeters; rads a deprecated unit of absorbed radiation dose, defined as 1 rad = 0.01 Gy = 0.01 J/kg; Roentgen a legacy unit of measurement for the exposure of X-rays; Each measure is often simply described as ‘dose’, which can lead to ...
Drugs come with a recommended dose in milligrams or micrograms per kilogram of body weight, and that is used in conjunction with the patient's age and body weight to determine a safe dose. In single-dose scenarios, the patient's body weight and the drug's recommended dose per kilogram are used to determine a safe one-time dose.
The c inj value is calculated as ratio of two independent measurements: the injected radioactivity (injected dose, ID) and the body weight (BW) of the subject. The ID can be estimated e.g. as difference in the radioactivity of the syringe before and after injection, if deemed necessary with correction for physical decay between each of those measurements and the time of injection.
Absolute bioavailability refers to the bioavailability of a drug when administered via an extravascular dosage form (i.e. oral tablet, suppository, subcutaneous, etc.) compared with the bioavailability of the same drug administered intravenously (IV). This is done by comparing the AUC of the non-intravenous dosage form with the AUC for the drug ...
The World Health Organization (WHO) has introduced a TDI for melamine as 0.2 milligrams (mg)/kg body weight (b.w.) as of 2008. [5] Similarly the established TDI range for dioxin according to WHO is 1-4 picograms toxic equivalency/kg body weight as of 1998. [6]
For substances that exhibit substantial plasma protein binding, clearance is generally dependent on the total concentration (free + protein-bound) and not the free concentration. [ 9 ] Most plasma substances have primarily their free concentrations regulated, which thus remains the same, so extensive protein binding increases total plasma ...