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The mammillary bodies also mamillary bodies, are a pair of small round brainstem nuclei. [2] They are located on the undersurface of the brain that, as part of the diencephalon, form part of the limbic system. They are located at the ends of the anterior arches of the fornix. [3]
The neopallium, also known as the superior or rational ("new mammalian") brain, comprises almost the whole of the hemispheres (made up of a more recent type of cortex, called neocortex) and some subcortical neuronal groups. It corresponds to the brain of the superior mammals, thus including the primates and, as a consequence, the human species.
The mammillary bodies directly or indirectly connect to the amygdala, hippocampus, and thalami as major structures in the limbic system. [6] The mammillothalamic tract carries signals from the mammillary bodies via the anterior thalamus to support spatial memory .
Its roof is represented by the floor of the third ventricle (i.e. posterior perforated substance, and the two mammillary bodies). Its floor is formed by the arachnoid membrane extending between the temporal lobes of either side. [2] Anteriorly, it extends to the optic chiasm. [1]
The posterior fibers (called the postcommissural fornix) of each side continue through the hypothalamus to the mammillary bodies; then to the anterior nuclei of thalamus via the mammillothalamic tract. The anterior fibers (precommissural fornix) end at the septal nuclei of the basal forebrain and nucleus accumbens of each half of the brain.
Brain at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (view tree for regions of the brain) BrainMaps.org; BrainInfo (University of Washington) "Brain Anatomy and How the Brain Works". Johns Hopkins Medicine. 14 July 2021. "Brain Map". Queensland Health. 12 July 2022.
Not from the actual human body, of course, but from the anatomical diagrams that purported to represent it. Goss was the esteemed editor of the 25th edition of the seminal classic Gray’s Anatomy . Internationally lauded as the authority on all things anatomical, Gray’s Anatomy had been considered essential for any would-be physician to own ...
The mammillary bodies are an important part of the Papez circuit. If there is damage, such as loss of neurons and/or myelination, to the mammillary bodies, the Papez circuit can be severely affected. There will be a disruption in the connecting parts of the system.