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SeHCAT is a taurine-conjugated bile acid analog which was synthesized for use as a radiopharmaceutical to investigate in vivo the enterohepatic circulation of bile salts. [2] By incorporating the gamma-emitter 75 Se into the SeHCAT molecule, the retention in the body or the loss of this compound into the feces could be studied easily using a standard gamma camera, available in most clinical ...
Taurine (/ ˈ t ɔː r iː n /), or 2-aminoethanesulfonic acid, is a non-proteinogenic naturally occurring amino sulfonic acid that is widely distributed in animal tissues. [1] It is a major constituent of bile and can be found in the large intestine , and accounts for up to 0.1% of total human body weight.
Taurine has an observed safe level of supplemental intake in normal healthy adults at up to 3 g/day. [2] Using the same level as an approximation for taurate yields a limit of 3.3 g/day for magnesium taurate, or alternatively 300 mg/day for elemental magnesium as taurate.
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UDCA and its taurine conjugates comprise about 47% of the bile in American black bears and up to 76% in Asiatic bears. [1] [3] Ursodeoxycholic acid and tauroursodeoxycholic acid were first chemically synthesized in 1954 in Japan. [1] Ursodeoxycholic acid is produced in several countries for the treatment of gallstones and primary biliary ...
Lysine. Technically, any organic compound with an amine (–NH 2) and a carboxylic acid (–COOH) functional group is an amino acid. The proteinogenic amino acids are a small subset of this group that possess a central carbon atom (α- or 2-) bearing an amino group, a carboxyl group, a side chain and an α-hydrogen levo conformation, with the exception of glycine, which is achiral, and proline ...
Acute Toxicity Basic Test is a procedure that measures the relative acute toxicity of a sample. This test is the best protocol for testing samples of unknown toxicity, a high level of toxicity, or when the test results are required to provide the highest confidence and precision.
The Escherichia coli tauD gene is required for the utilization of taurine (2-aminoethanesulfonic acid) as a sulfur source and is expressed only under conditions of sulfate starvation. TauD is an alpha-ketoglutarate-dependent dioxygenase catalyzing the oxygenolytic release of sulfite from taurine. [ 1 ]