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  2. Lupus nephritis - Wikipedia

    en.wikipedia.org/wiki/Lupus_nephritis

    The proliferative forms of lupus nephritis are associated with a higher risk of progression to end stage kidney disease. [21] Black and Hispanic people with lupus nephritis are more likely to present with severe disease at initial presentation (with more proteinuria and more extensive histopathologic changes) and progress to end stage kidney ...

  3. Chronic kidney disease - Wikipedia

    en.wikipedia.org/wiki/Chronic_kidney_disease

    Fluid overload symptoms may range from mild edema to life ... and lupus nephritis; Tubulointerstitial disease includes ... of life, life expectancy, ...

  4. Childhood-onset systemic lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Childhood-onset_systemic...

    Nonetheless, a study in 2013 reported that cSLE patients with lupus nephritis had a 19-fold higher mortality rate while aSLE patients with lupus nephritis had an 8-fold higher mortality rate than their respective age-matched populations [7] [82] and a study in 2020 suggested that the survival rate of lupus nephritis in children and adults has ...

  5. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Lupus, formally called systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. [1] Symptoms vary among people and may be mild to severe. [ 1 ]

  6. Roivant Sciences' lupus drug fails to reduce symptoms in mid ...

    www.aol.com/news/roivant-sciences-lupus-drug...

    The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...

  7. Nephritis - Wikipedia

    en.wikipedia.org/wiki/Nephritis

    Worldwide, the highest rates [clarification needed] of nephritis are 50–55% for African or Asian descent followed by Hispanic at 43% and Caucasian at 17%. [20] The average age of an individual diagnosed with kidney inflammation (in this case, lupus nephritis) is 28.4 years old. [21]

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