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Fluorescein is a dye which is taken up by damaged cornea such that the area appears green under cobalt blue light. [3] There is also a version that comes premixed with lidocaine. [4] [8] Fluorescein was first made in 1871. [9] It is on the World Health Organization's List of Essential Medicines. [10]
Fluorescein can be introduced to a plant's veins through the roots or a cut stem. The dye is able to be taken up into the plant the same way as water and moves from the roots to the top of the plant due to a transpirational pull. [29] The fluorescein that has been taken up into the plant can be visualized under a fluorescent microscope.
The fluorescein is administered intravenously in intravenous fluorescein angiography (IVFA) and orally in oral fluorescein angiography (OFA). The test is a dye tracing method. The fluorescein dye also reappears in the patient urine, causing the urine to appear darker, and sometimes orange. [2] It can also cause discolouration of the saliva.
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
A carboxyfluorescein molecule is a fluorescein molecule with a carboxyl group added. They are commonly used as a tracer agents. It is used in the sequencing of nucleic acids and in the labeling of nucleotides. Commercially available FAM is a mixture of two isomers, 5-FAM and 6-FAM, and the correct name is 5(6)-carboxyfluorescein.
Nearly half of U.S. adults still believe that the benefits of taking low-dose aspirin daily outweighs the risks — despite new guidance that suggests otherwise, according to a new survey. The ...
Free Gd 3+ has a median lethal dose of 0.34 mmol/kg (IV, mouse) [27] or 100–200 mg/kg, but the LD50 is increased by a factor of 31 times [28] when Gd 3+ is chelated. [ 29 ] The spectrum of adverse drug reactions is greater with gadolinium-based contrast agents than with iodinated contrast agents ( radiocontrast agents ).
The fluorescein is examined with a cobalt blue filter. At this point, the fluorescein appears green in color. Any changes in color or surface of the fluorescence area indicate the presence of corneal leakage. The test is contraindicated in obvious globe rupture, Full-thickness eye laceration, and fluorescein hypersensitivity. [1]