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In a typical set of rules, a platelet donor must weigh at least 50 kg (110 lb) and have a platelet count of at least 150 x 10 9 /L (150,000 platelets per mm³). [2] One unit has greater than 3×10 11 platelets. Therefore, it takes 2 liters of blood having a platelet count of 150,000/mm³ to produce one unit of platelets.
Platelets are either isolated from collected units of whole blood and pooled to make a therapeutic dose, or collected by platelet apheresis: blood is taken from the donor, passed through a device which removes the platelets, and the remainder is returned to the donor in a closed loop. The industry standard is for platelets to be tested for ...
Aggregation of thrombocytes (platelets). Platelet-rich human blood plasma (left vial) is a turbid liquid. Upon addition of ADP, platelets are activated and start to aggregate, forming white flakes (right vial). Hemostasis occurs when blood is present outside of the body or blood vessels.
Side effects can include allergic reactions such as anaphylaxis, infection, and lung injury. [2] Bacterial infections are relatively more common with platelets as they are stored at warmer temperatures. [2] Platelets can be produced either from whole blood or by apheresis. [1] They keep for up to five to seven days. [1]
The automated red blood cell collection procedure for donating erythrocytes is referred to as 'Double Reds' or 'Double Red Cell Apheresis.' [9] Plateletpheresis (thrombapheresis, thrombocytapheresis) – blood platelets. Plateletpheresis is the collection of platelets by apheresis while returning the RBCs, WBCs, and component plasma.
One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/μL. [5] Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known). [6] [7]
The scion of the same blue-blood family that produced President Franklin Delano Roosevelt, Griffiths was the psychedelic counterculture's dream spokesman: a clean-cut "scientist's scientist," so ...
They circulate in the blood of mammals and are involved in hemostasis, leading to the formation of blood clots. Platelets release thread-like fibers to form these clots. The normal range (99% of population analyzed) for platelets is 150,000 to 450,000 per cubic millimeter. [6] If the number of platelets is too low, excessive bleeding can occur.
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