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The protection provided by the foreskin for the glans penis and meatus has been recognized since 1915. In the absence of the foreskin the meatus is exposed to mechanical and chemical irritation from ammoniacal diaper (nappy) that produces blister formation and ulceration of the urethral opening, which eventually gives rise to meatal stenosis (a narrowing of the opening). [1]
A urethral stricture is a narrowing of the urethra, the tube connected to the bladder that allows urination. The narrowing reduces the flow of urine and makes it more difficult or even painful to empty the bladder. [1] Urethral stricture is caused by injury, instrumentation, infection, and certain non-infectious forms of urethritis. The ...
Around one third of men will develop urinary tract (outflow) symptoms, of which the principal underlying cause is benign prostatic hyperplasia. [26] Once symptoms arise, their progress is variable and unpredictable with about one third of patients improving, one third remaining stable and one third deteriorating. [citation needed]
Stenosis (from Ancient Greek στενός (stenós) 'narrow') is the abnormal narrowing of a blood vessel or other tubular organ or structure such as foramina and canals. It is also sometimes called a stricture (as in urethral stricture ).
Urethral syndrome is defined as symptoms suggestive of a lower urinary tract infection but in the absence of significant bacteriuria with a conventional pathogen. [1] It is a diagnosis of exclusion in patients with dysuria and frequency without demonstrable infection. [2] In women, vaginitis should also be ruled out. [3]
It may initially cause no symptoms. [28] In later stages, it can lead to difficulty urinating, blood in the urine or pain in the pelvis, back, or when urinating. [31] A disease known as benign prostatic hyperplasia may produce similar symptoms. [28] Other late symptoms may include feeling tired due to low levels of red blood cells. [28]