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A 2007 Cochrane review assessed the side effects of short-term use of pseudoephedrine at recommended doses as a nasal decongestant. [21] It found that pseudoephedrine had a small risk of insomnia and this was the only side effect that occurred at rates significantly different from placebo. [21]
Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
Pseudoephedrine acts indirectly on the adrenergic receptor system, whereas phenylephrine and oxymetazoline are direct agonists. The effects are not limited to the nose, and these medicines may cause hypertension (high blood pressure) through vasoconstriction; it is for this reason that people with hypertension are advised to avoid them. Most ...
Stimulants such as epinephrine, [40] theophylline and salbutamol [41] orally have been used to treat asthma, but inhaled adrenergic drugs are now preferred due to less systemic side effects. Pseudoephedrine is used to relieve nasal or sinus congestion caused by the common cold, sinusitis, hay fever and other respiratory allergies; it is also ...
Common side effects of nasal spray may include headache, dry nose, dry mouth or throat, nasal or throat irritation, nosebleeds, bad taste in mouth, nausea, dizziness, or constipation. [7] Potentially serious side effects are unusual, but include severe allergic reaction, eye pain or change in vision, or urinary retention.
Common side effects include sleepiness, constipation, and dry mouth. [10] Other side effects may include low blood pressure and urinary problems. [11] It appears to work by activating α 2A-adrenergic receptors in the brain, thereby decreasing sympathetic nervous system activity. [10]
The medication takes effect within two hours and lasts for about 4–6 hours. [2] It is a first-generation antihistamine and works by blocking the histamine H 1 receptor. [2] Common side effects include sleepiness, restlessness, and weakness. Other side effects may include dry mouth and wheeziness. [2]
Side effects in dogs and cats include hypersalivation, diarrhea, loss of appetite, and vomiting. [12] [16] Eight percent of dogs taking maropitant at doses meant to prevent motion sickness vomited right after, likely due to the local effects maropitant had on the gastrointestinal tract. Small amounts of food beforehand can prevent such post ...