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Having ketone bodies in the urine; a warning sign of diabetic ketoacidosis (DKA). Ketone test strips can be used to detect them. Ketosis fat metabolism. It is characteristic of ordinary metabolism, when glucose is not available, but can become abnormal, leading to ketoacidosis under some conditions.
Ketosis is a metabolic state characterized by elevated levels of ketone bodies in the blood or urine. Physiological ketosis is a normal response to low glucose availability. . In physiological ketosis, ketones in the blood are elevated above baseline levels, but the body's acid–base homeostasis is maintain
It is seen in conditions in which the body produces excess ketones as an indication that it is using an alternative source of energy. It is seen during starvation or more commonly in type 1 diabetes mellitus. Production of ketone bodies is a normal response to a shortage of glucose, meant to provide an alternate source of fuel from fatty acids.
Ascorbic acid (vitamin C) is known to interfere with the oxidation reaction of the blood and glucose pad on common urine test strips. Some urine test strips are protected against the interference with iodate, which eliminates ascorbic acid by oxidation. [25] Some test strips include a test for urinary ascorbate.
Test strips for glucose contain the enzyme glucose oxidase, which breaks down glucose and forms hydrogen peroxide as a byproduct. In the presence of a peroxidase enzyme, hydrogen peroxide reacts with a chromogen to induce a color change. [51] The presence of glucose in the urine is known as glycosuria.
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