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Elastin is a protein encoded by the ELN gene in humans and several other animals. Elastin is a key component in the extracellular matrix of gnathostomes (jawed vertebrates). [ 5 ] It is highly elastic and present in connective tissue of the body to resume its shape after stretching or contracting. [ 6 ]
Skin elastosis causes Condition Distinctive features Histopathology Actinic elastosis (most common, also called solar elastosis) Elastin replacing collagen fibers of the papillary dermis and reticular dermis: Elastosis perforans serpiginosa: Degenerated elastic fibers and transepidermal perforating canals (arrow in image points at one of them) [18]
Actinic elastosis, also known as solar elastosis, is an accumulation of abnormal elastin (elastic tissue) in the dermis of the skin, [2] or in the conjunctiva of the eye, [3] which occurs as a result of the cumulative effects of prolonged and excessive sun exposure, a process known as photoaging.
With increasing tissue deformation the collagen is gradually stretched in the direction of deformation. When taut, these fibers produce a strong growth in tissue stiffness. The composite behavior is analogous to a nylon stocking, whose rubber band does the role of elastin as the nylon does the role of collagen. In soft tissues, the collagen ...
Skin care is a routine daily procedure in many settings, such as skin that is either too dry or too moist, and prevention of dermatitis and prevention of skin injuries. [ 3 ] Skin care is a part of the treatment of wound healing , radiation therapy and some medications.
Lysyl oxidase has also proven crucial to the development of the respiratory system and the skin, as collagen and elastin represent 50-60% of the composition of the lung, and 75% of the skin. In Lox homozygous null models ( Lox -/- ), the activity of LOX was reduced by up to 80%, and the phenotype of the lungs resembles those of patients with ...
Pig skin especially shares similar epidermal and dermal thickness ratios to human skin: pig and human skin share similar hair follicle and blood vessel patterns; biochemically the dermal collagen and elastin content is similar in pig and human skin; and pig skin and human skin have similar physical responses to various growth factors.
Collagen and elastin are proteins in the skin that contribute to the skin's strength, resilience, flexibility, and help skin that has been stretched to recover its original state. Boosting the production of collagen and elastin helps prevent stretch marks from occurring. [18] Stretch marks can also derive from nutritional deficiencies.