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The brain is enormously costly to the rest of the body, in terms of oxygen and nutrient consumption. It can require up to 20 percent of the body's energy—more than any other organ—despite making up only 2 percent of the human body weight.
Early experiments showed that adrenaline increases twitch, but not tetanic force and rate of force development in muscles. [38]One proposed explanation is Tim Noakes' "central governor" theory, which states that higher instances in the central nervous system dynamically and subconsciously control the number of active motor units in the muscle.
The brain requires approximately 3.3 ml of oxygen per 100 g of brain tissue per minute. Initially, the body responds to lowered blood oxygen by redirecting blood to the brain and increasing cerebral blood flow. Blood flow may increase up to twice the normal flow but no more. If the increased blood flow is sufficient to supply the brain's oxygen ...
The blood–brain barrier is formed by the brain capillary endothelium and excludes from the brain 100% of large-molecule neurotherapeutics and more than 98% of all small-molecule drugs. [28] Overcoming the difficulty of delivering therapeutic agents to specific regions of the brain presents a major challenge to treatment of most brain disorders.
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Use of a clock or timer is recommended to keep accurate times, the number of rounds, and intensity. An alternative form of HIIT, designed for heart rate training, involves a 30-minute period of cardio followed by 30 minutes of full-body resistance training to help maximize calorie burning. [15]