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The new multiple range test proposed by Duncan makes use of special protection levels based upon degrees of freedom.Let , = be the protection level for testing the significance of a difference between two means; that is, the probability that a significant difference between two means will not be found if the population means are equal.
To determine if there is a significant difference between two means with equal sample sizes, the Newman–Keuls method uses a formula that is identical to the one used in Tukey's range test, which calculates the q value by taking the difference between two sample means and dividing it by the standard error:
Tukey's range test, also known as Tukey's test, Tukey method, Tukey's honest significance test, or Tukey's HSD (honestly significant difference) test, [1] is a single-step multiple comparison procedure and statistical test.
From the t-test, the difference between the group means is 6-2=4. From the regression, the slope is also 4 indicating that a 1-unit change in drug dose (from 0 to 1) gives a 4-unit change in mean word recall (from 2 to 6). The t-test p-value for the difference in means, and the regression p-value for the slope, are both 0.00805. The methods ...
A paired difference test, better known as a paired comparison, is a type of location test that is used when comparing two sets of paired measurements to assess whether their population means differ. A paired difference test is designed for situations where there is dependence between pairs of measurements (in which case a test designed for ...
In a confirmatory or primary screen with replicates, for the i-th test compound with replicates, we calculate the paired difference between the measured value (usually on the log scale) of the compound and the median value of a negative control in a plate, then obtain the mean ¯ and variance of the paired difference across replicates.
The mean difference is the estimated bias, and the SD of the differences measures the random fluctuations around this mean. If the mean value of the difference differs significantly from 0 on the basis of a 1-sample t-test, this indicates the presence of fixed bias. If there is a consistent bias, it can be adjusted for by subtracting the mean ...
A simple (not necessarily orthogonal) contrast is the difference between two means. A more complex contrast can test differences among several means (ex. with four means, assigning coefficients of –3, –1, +1, and +3), or test the difference between a single mean and the combined mean of several groups (e.g., if you have four means assign ...
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