Search results
Results From The WOW.Com Content Network
Trimethobenzamide synthesis: Hoffmann La Roche, U.S. patent 2,879,293 (1959). Alkylation of the sodium salt of p -hydroxybenzaldehyde (1) with 2-dimethylaminoethyl chloride affords the ether (2). Reductive amination of the aldehyde in the presence of ammonia gives diamine (3).
Cyamemazine differs from other phenothiazine neuroleptics in that aside from the usual profile of dopamine, α 1-adrenergic, H 1, and mACh receptor antagonism, [9] it additionally produces potent blockade of several serotonin receptors, including 5-HT 2A, 5-HT 2C, and 5-HT 7.
1 Side effects. 2 Drug interactions. 3 Synthesis. 4 References. Toggle the table of contents. ... [5] Majeptil is available in 10 mg tablets. [6] Side effects. Common [7]
3,4,5-Trimethoxybenzaldehyde can be used as an intermediate in the synthesis of some pharmaceutical drugs including trimethoprim, [1] [2] cintriamide, roletamide, trimethoquinol (aka tretoquinol), and trimazosin as well as some psychedelic phenethylamines.
Benzyltrimethylammonium hydroxide, also known as Triton B or trimethylbenzylammonium hydroxide, is a quaternary ammonium salt that functions as an organic base. It is usually handled as a solution in water or methanol.
Sulpiride, sold under the brand name Dogmatil among others, is an atypical antipsychotic (although some texts have referred to it as a typical antipsychotic) [10] medication of the benzamide class which is used mainly in the treatment of psychosis associated with schizophrenia and major depressive disorder, and is sometimes used in low dosage to treat anxiety and mild depression.
Metopimazine is an approved prescription drug in France under the brand name Vogalene® [8] that has been used for the treatment of nausea and vomiting. [9] Vogalene® is available under different forms, including 15 mg capsules, 7.5 mg orally disintegrating tablets, 5 mg suppository, 0.1% oral liquid, and a 10 mg/mL intravenous (IV) solution approved for the prevention of chemotherapy-induced ...
THF is an essential precursor in the thymidine synthesis pathway and interference with this pathway inhibits bacterial DNA synthesis. [24] Trimethoprim's inhibitory activity for bacterial dihydrofolate reductase is sixty thousand times greater than for human dihydrofolate reductase. [ 25 ]