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Plaque build-up often doesn’t cause symptoms, but it can block blood flow to vital organs like your heart. Coronary artery disease occurs when atherosclerosis affects the arteries supplying ...
Coronary artery disease develops when the arteries that supply your heart become clogged with a fatty substance called plaque. The build-up of plaque is also called atherosclerosis.
What Causes Clogged Arteries? Much of the blame for clogged arteries comes down to diet, according to Dr. Briana Costello, MD , general and interventional cardiologist at The Texas Heart Institute .
Symptoms include chest pain or angina, shortness of breath, and fatigue. [6]A completely blocked coronary artery will cause a heart attack. [6] Common heart attack symptoms include chest pain or angina, pain or discomfort that spreads to the shoulder, arm, back, neck jaw, teeth or the upper belly, cold sweats, fatigue, heartburn, nausea, shortness of breath, or lightheadedness.
This blood clot may then restrict blood flow within the heart, leading to heart tissue damage, or a myocardial infarction, also known as a heart attack. [ 1 ] Coronary thrombosis is most commonly caused as a downstream effect of atherosclerosis , a buildup of cholesterol and fats in the artery walls.
A myocardial infarction (MI), or heart attack, arises from complete occlusion of a coronary artery. [9] The most frequent cause of MI is the rupturing of an atherosclerotic plaque formed in CAD. Plaque rupture exposes the subendothelial matrix beneath the plaque, initiating thrombus formation within the vasculature. [7]
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