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  2. Metronomic therapy - Wikipedia

    en.wikipedia.org/wiki/Metronomic_therapy

    In conventional chemotherapy, a dose close to the maximum tolerated dose is administered in a bolus manner to achieve cytotoxic effects on tumor cells. [5] However, the side effects are often significant as the cytotoxic agents also kill the fast-dividing cells normally present in the body, such as bone marrow cells and epithelial cells of the gastrointestinal tract. [6]

  3. Percentage depth dose curve - Wikipedia

    en.wikipedia.org/wiki/Percentage_depth_dose_curve

    The dose values are divided by the maximum dose, referred to as d max, yielding a plot in terms of percentage of the maximum dose. Dose measurements are generally made in water or "water equivalent" plastic with an ionization chamber, since water is very similar to human tissue with regard to radiation scattering and absorption.

  4. Dose-dense chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Dose-dense_chemotherapy

    Dose-dense chemotherapy is a chemotherapy treatment plan in which drugs are given with less time between treatments than in a standard chemotherapy treatment plan. [ 1 ] The Gompertzian model of tumor cell growth shows tumor cells growing fastest when the tumor is small.

  5. Chemotherapy - Wikipedia

    en.wikipedia.org/wiki/Chemotherapy

    The devices have different applications regarding duration of chemotherapy treatment, method of delivery and types of chemotherapeutic agent. [7]: 94–95 Depending on the person, the cancer, the stage of cancer, the type of chemotherapy, and the dosage, intravenous chemotherapy may be given on either an inpatient or an outpatient basis. For ...

  6. High-dose chemotherapy - Wikipedia

    en.wikipedia.org/wiki/High-dose_chemotherapy

    Recently, there has been a change in cancer treatment toward less toxic, more customized regimens. Metronomic chemotherapy, which involves regularly giving patients low dosages of chemotherapy drugs, is one instance of this. [46] This technique has been shown to have the potential to change the tumor microenvironment and limit tumor growth. [47]

  7. Area under the curve (pharmacokinetics) - Wikipedia

    en.wikipedia.org/wiki/Area_under_the_curve...

    Absolute bioavailability refers to the bioavailability of a drug when administered via an extravascular dosage form (i.e. oral tablet, suppository, subcutaneous, etc.) compared with the bioavailability of the same drug administered intravenously (IV). This is done by comparing the AUC of the non-intravenous dosage form with the AUC for the drug ...

  8. Gray (unit) - Wikipedia

    en.wikipedia.org/wiki/Gray_(unit)

    The International Committee for Weights and Measures states: "In order to avoid any risk of confusion between the absorbed dose D and the dose equivalent H, the special names for the respective units should be used, that is, the name gray should be used instead of joules per kilogram for the unit of absorbed dose D and the name sievert instead ...

  9. Dose-volume histogram - Wikipedia

    en.wikipedia.org/wiki/Dose-volume_histogram

    The total volume of the organ that receives a certain dose is plotted in the appropriate dose bin. [5] This volume is determined by the total number of voxels characterized by a specified range of dosage for the organ considered. The differential DVH provides information about changes in dose within the structure considered as well as ...

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