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Yescarta is a Chimeric Antigen Receptor (CAR) T cell therapy, also known as CAR-T. Moffitt Cancer Center's Frederick Locke, is the co-lead investigator of the pivotal ZUMA-1 clinical trial that tested the new therapy, which is manufactured by Kite, a Gilead company. [32]
CARs targeting BCMA were initially reported by Robert Carpenter and James Kochenderfer et al. [35] [36] Anti-BCMA CAR T cells have now been tested in many clinical trials, and anti-BCMA CAR T-cell products have been approved by the U.S. Food and Drug Administration. [37] [38] [39] CAR T cells have also been found to be effective in treating ...
The company employs over 8,200 staff and 1,920 physicians in their outpatient facilities and four hospitals. [citation needed] Mount Carmel East opened in 1972 near Reynoldsburg. [1]
CAR-T therapy exhibits distinct specificity compared to other adaptive immunotherapies and traditional cancer treatments such as chemotherapy. [8] CAR-T kill tumor cells specifically by targeting the tumor-associated antigens to keep the damage to healthy tissue at a minimum level.
The expanded maternity unit is designed to handle 3,500 deliveries a year. The expansion of the heart center included two operating rooms and many cardiology upgrades allowing it to function as a fully functioning emergency cardiac treatment center. Following this, in July 2003, an $18 million project to expand the emergency room was completed. [9]
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