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Magnetic reluctance, or magnetic resistance, is a concept used in the analysis of magnetic circuits. It is defined as the ratio of magnetomotive force (mmf) to magnetic flux . It represents the opposition to magnetic flux, and depends on the geometry and composition of an object.
Nucleic acid NMR is the use of nuclear magnetic resonance spectroscopy to obtain information about the structure and dynamics of nucleic acid molecules, such as DNA or RNA.It is useful for molecules of up to 100 nucleotides, and as of 2003, nearly half of all known RNA structures had been determined by NMR spectroscopy.
In 2010, Arnd Pralle and colleges showed that the first in vivo magneto-thermal stimulation of heat sensitive ion channel TRPV1 that employs magnetic nanoparticles as a transducer in C. elegans. [4] In 2012, Seung Chan Kim showed gene expression profile change of total human genome approximately 30,000 genes using 0.2T static magnetic fields. [5]
Immunomagnetic separation (IMS) is a laboratory tool that can efficiently isolate cells out of body fluid or cultured cells. It can also be used as a method of quantifying the pathogenicity of food, blood or feces. DNA analysis have supported the combined use of both this technique and Polymerase Chain Reaction (PCR). [1]
Magnet-assisted transfection is a transfection method which uses magnetic interactions to deliver DNA into target cells. Nucleic acids are associated with magnetic nanoparticles, and magnetic fields drive the nucleic acid-particle complexes into target cells, where the nucleic acids are released. [1] [2]
Magnetobiology is the study of biological effects of mainly weak static and low-frequency magnetic fields, which do not cause heating of tissues. Magnetobiological effects have unique features that obviously distinguish them from thermal effects; often they are observed for alternating magnetic fields just in separate frequency and amplitude intervals.
It is the property of certain substances or phenomena that give rise to magnetic fields: =, where Φ is the magnetic flux and is the reluctance of the circuit. It can be seen that the magnetomotive force plays a role in this equation analogous to the voltage V in Ohm's law , V = IR , since it is the cause of magnetic flux in a magnetic circuit ...
Experimental approaches of determining the structure of nucleic acids, such as RNA and DNA, can be largely classified into biophysical and biochemical methods. Biophysical methods use the fundamental physical properties of molecules for structure determination, including X-ray crystallography, NMR and cryo-EM.