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LIMMA provides a set of tools for background correction and scaling, as well as an option to average on-slide duplicate spots. [5] A common method for evaluating how well normalized an array is, is to plot an MA plot of the data. MA plots can be produced using programs and languages such as R and MATLAB. [6] [7]
In statistics, a moving average (rolling average or running average or moving mean [1] or rolling mean) is a calculation to analyze data points by creating a series of averages of different selections of the full data set. Variations include: simple, cumulative, or weighted forms. Mathematically, a moving average is a type of convolution.
[1] [2] Many notable mean operators such as the max, arithmetic average, median and min, are members of this class. They have been widely used in computational intelligence because of their ability to model linguistically expressed aggregation instructions.
This algorithm can easily be adapted to compute the variance of a finite population: simply divide by n instead of n − 1 on the last line.. Because SumSq and (Sum×Sum)/n can be very similar numbers, cancellation can lead to the precision of the result to be much less than the inherent precision of the floating-point arithmetic used to perform the computation.
Exponential smoothing or exponential moving average (EMA) is a rule of thumb technique for smoothing time series data using the exponential window function. Whereas in the simple moving average the past observations are weighted equally, exponential functions are used to assign exponentially decreasing weights over time. It is an easily learned ...
In computer science, the median of medians is an approximate median selection algorithm, frequently used to supply a good pivot for an exact selection algorithm, most commonly quickselect, that selects the kth smallest element of an initially unsorted array.
MATLAB allows matrix manipulations, plotting of functions and data, implementation of algorithms, creation of user interfaces, and interfacing with programs written in other languages. Although MATLAB is intended primarily for numeric computing, an optional toolbox uses the MuPAD symbolic engine allowing access to symbolic computing abilities.
The basis behind array programming and thinking is to find and exploit the properties of data where individual elements are similar or adjacent. Unlike object orientation which implicitly breaks down data to its constituent parts (or scalar quantities), array orientation looks to group data and apply a uniform handling.