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Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954.
In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. [ 1 ] [ 2 ] Other terms include transaminasemia , [ 3 ] and elevated liver enzymes (though they are not the only enzymes in the liver).
The Air Tractor AT-1002 is a single-seat agricultural and firefighting aircraft made by American aircraft manufacturer Air Tractor. The aircraft is the company's largest, with a takeoff and landing weight of 20,000 pounds and useful load of 10,800 pounds. The aircraft can carry over 1,060 gallons of fire retardant or 335 gallons of agricultural ...
The AST/ALT ratio increases in liver functional impairment. In alcoholic liver disease, the mean ratio is 1.45, and mean ratio is 1.33 in post necrotic liver cirrhosis. Ratio is greater than 1.17 in viral cirrhosis, greater than 2.0 in alcoholic hepatitis, and 0.9 in non-alcoholic hepatitis.
Hepatic artery thrombosis may cause severe elevations in serum aminotransferases, alanine transaminase (ALT) and aspartate transaminase (AST). [4] Often the AST is greater than the ALT. [ 4 ] Hepatic artery thrombosis is usually diagnosed with ultrasound with doppler , although it may be diagnosed using computed tomography (CT) or magnetic ...
Alanine transaminase (ALT), also known as alanine aminotransferase (ALT or ALAT), formerly serum glutamate-pyruvate transaminase (GPT) or serum glutamic-pyruvic transaminase (SGPT), is a transaminase enzyme (EC 2.6.1.2) that was first characterized in the mid-1950s by Arthur Karmen and colleagues. [1]
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00:00 UTC (7:00 p.m. AST, December 4) – A subtropical storm develops from an area of low pressure about 385 mi (620 km) south of the Azores and simultaneously attains its peak intensity with maximum sustained winds of 50 mph (85 km/h) and a minimum barometric pressure of 997 mb (hPa; 29.44 inHg).