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[3] [2] At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout. [ 3 ] Cause 3
If you have frequent gout flares, gout associated with tophi, or joint damage, your provider may prescribe medication to lower uric acid levels. These can help prevent gout flares and further ...
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a single red, tender, hot, and swollen joint. [ 1 ] [ 2 ] Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. [ 3 ]
[1] [2] [12] Once the acute attack subsides, levels of uric acid can be lowered via lifestyle changes and in those with frequent attacks, allopurinol or probenecid provides long-term prevention. [5] Taking vitamin C and having a diet high in low-fat dairy products may be preventive. [13] [14] Gout affects about 1–2% of adults in the developed ...
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
In human blood plasma, the reference range of uric acid is typically 3.4–7.2 mg per 100 mL(200–430 μmol/L) for men, and 2.4–6.1 mg per 100 mL for women (140–360 μmol/L). [34] Uric acid concentrations in blood plasma above and below the normal range are known as, respectively, hyperuricemia and hypouricemia.