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PDE5 inhibitors are contraindicated within 24 hours (or 48 hours with tadalafil) of taking alpha-blockers, soluble guanylate cyclase stimulators, or nitrate medications such as isosorbide mononitrate or isosorbide dinitrate. [1] Concurrent use of these medications can lead to life-threatening low blood pressure. [5]
Brand-name ED drugs like Cialis (tadalafil), Levitra(vardenafil), Stendra and others that are FDA-approved to treat ED are also not safe to use without medical advice.
Other medications that can interact with oral ED medicine include alpha blockers used to manage hypertension (high blood pressure) and other anti-hypertensive medications. They should only be ...
The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.
Sildenafil's brand name, Viagra, is widely recognized in popular culture, and the drug's association with treating erectile dysfunction has led to its recreational use. [33] The reasons behind such use include the belief that the drug increases libido, improves sexual performance, [ 33 ] or permanently increases penis size. [ 34 ]
Dipyridamole has been shown to lower pulmonary hypertension without significant drop of systemic blood pressure. It inhibits proliferation of smooth muscle cells in vivo and modestly increases unassisted patency of synthetic arteriovenous hemodialysis grafts.