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  2. Atorvastatin - Wikipedia

    en.wikipedia.org/wiki/Atorvastatin

    Statins with shorter half-lives are more effective when taken in the evening, so their peak effect occurs when the body's natural cholesterol production is at its highest. A recent meta-analysis suggested that statins with longer half-lives, including atorvastatin, may also be more effective at lowering LDL cholesterol if taken in the evening. [38]

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    On average, statins can lower LDL cholesterol by 1.8 mmol/L (70 mg/dL), which translates into an estimated 60% decrease in the number of cardiac events (heart attack, sudden cardiac death) and a 17% reduced risk of stroke after long-term treatment. [36] A greater benefit is observed with high-intensity statin therapy. [37]

  4. Clearance (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Clearance_(pharmacology)

    Clearance of a substance is sometimes expressed as the inverse of the time constant that describes its removal rate from the body divided by its volume of distribution (or total body water). In steady-state, it is defined as the mass generation rate of a substance (which equals the mass removal rate) divided by its concentration in the blood.

  5. Discovery and development of statins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Type 2 statins Statins that are fully synthetic and have larger groups linked to the HMG-like moiety are often referred to as type 2 statins. One of the main differences between the type 1 and type 2 statins is the replacement of the butyryl group of type 1 statins by the fluorophenyl group of type 2 statins. This group is responsible for ...

  6. Hyperlipidemia - Wikipedia

    en.wikipedia.org/wiki/Hyperlipidemia

    Hyperlipidemia is abnormally high levels of any or all lipids (e.g. fats, triglycerides, cholesterol, phospholipids) or lipoproteins in the blood. [2] The term hyperlipidemia refers to the laboratory finding itself and is also used as an umbrella term covering any of various acquired or genetic disorders that result in that finding. [3]

  7. Everything you need to know about the Mayo Clinic diet - AOL

    www.aol.com/lifestyle/everything-know-mayo...

    The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...

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    Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!

  9. How Long Can Mayo Sit Out? - AOL

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    It’s a scenario we’ve seen too many times: You’re hosting a family barbecue and Aunt Doreen brings her famous potato salad. It’s creamy, dreamy and everything you want to pair with a hot ...