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  2. T-cell acute lymphoblastic leukemia - Wikipedia

    en.wikipedia.org/wiki/T-cell_acute_lymphoblastic...

    In childhood, T-cell acute lymphoblastic leukemia (T-ALL) patients can expect a 5-year event-free survival (EFS) rate of 70% and an overall survival (OS) rate of 80%. [1] Among the approximately 25% of children who relapse, survival rates drop to 30-50%, with patients generally showing a much poorer prognosis. [ 1 ]

  3. T-cell prolymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/T-cell_prolymphocytic_leukemia

    T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver, spleen, and skin involvement. [1] T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic leukemias in adults. [2]

  4. T-cell leukemia - Wikipedia

    en.wikipedia.org/wiki/T-cell_leukemia

    T-cell leukemia describes several different types of lymphoid leukemia which affect T cells. Types include: [1] Large granular lymphocytic leukemia; Adult T-cell leukemia/lymphoma; T-cell prolymphocytic leukemia; In practice, it can be hard to distinguish T-cell leukemia from T-cell lymphoma, and they are often grouped together.

  5. Acute lymphoblastic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_lymphoblastic_leukemia

    In a 22-day process, the "drug" is customized for each person. T cells purified from each person are modified by a virus that inserts genes that encode a chimaeric antigen receptor into their DNA, one that recognizes leukemia cells. [63] Obecabtagene autoleucel (Aucatzyl) was approved for medical use in the United States in November 2024. [64] [65]

  6. Adult T-cell leukemia/lymphoma - Wikipedia

    en.wikipedia.org/wiki/Adult_T-cell_leukemia/lymphoma

    Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare cancer of the immune system's T-cells [1] [2] [3] caused by human T cell leukemia/lymphotropic virus type 1 (). [4] All ATL cells contain integrated HTLV-1 provirus further supporting that causal role of the virus in the cause of the neoplasm. [4]

  7. Childhood leukemia - Wikipedia

    en.wikipedia.org/wiki/Childhood_Leukemia

    The 5-year survival rate for children with leukemia is 83.6% in the USA. This means that 83.6% of children diagnosed with leukemia live for 5 years or more after their diagnosis. This is greatly improved from a 5-year survival rate of 36.5% in 1975. The improvement is largely attributed to advances in therapy, particularly therapy for ALL.

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