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Pimobendan is indicated for the management of the signs of mild, moderate, or severe congestive heart failure in dogs due to clinical myxomatous mitral valve disease (MMVD) or dilated cardiomyopathy (DCM); [1] [7] and for use with concurrent therapy for congestive heart failure (e.g.,furosemide, etc.) as appropriate on a case-by-case basis. [1]
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The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...
UpCard-CA1 (torsemide oral solution) was conditionally approved for use with concurrent therapy with pimobendan, spironolactone, and an angiotensin-converting enzyme (ACE) inhibitor for the management of pulmonary edema (fluid build-up in lungs) in dogs with congestive heart failure caused by myxomatous mitral valve disease (MMVD). [17] [18]
Experimental studies on rats and dogs, proved the efficacy and mechanism of action of omecamtiv mecarbil. [4] Clinical studies on humans have shown there is a direct linear relationship between dose and systolic ejection time. [2] [13] [14] The dose-dependent effects persisted throughout the entire trial, suggesting that desensitization does ...
Jolene: The pit bull mix requires a wheelchair to get around."But she really moves around the field," says Schachner. Trio: The three-legged Boston Terrier bounds with the speed of a jackrabbit.
Here are links to possibly useful sources of information about Pimobendan. PubMed provides review articles from the past five years (limit to free review articles ) The TRIP database provides clinical publications about evidence-based medicine .
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