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One factor that causes mood disturbance is fluctuation of milieu hormones [143] including sex steroids, growth hormones, stress hormones, etc. [144] [145] Major depression : Major depression is a disorder with symptoms such as feelings of sadness, loss of interest, emptiness [ 146 ] and, for some people, mixed with irritability, mental ...
In addition, the person may experience one or more of the following emotions: sadness, emptiness, hopelessness, indifference, anxiety, tearfulness, pessimism, emotional numbness, or irritability. [1] [3] In children and adolescents, a depressed mood often presents as irritability. [1]
[7] [5] [8] During periods of depression, the individual may experience crying, have a negative outlook on life, and demonstrate poor eye contact with others. [4] The risk of suicide is high. Over a period of 20 years, 6% of those with bipolar disorder died by suicide, [4] with about one-third attempting suicide in their lifetime. [5]
Bipolar I disorder (BD-I; pronounced "type one bipolar disorder") is a type of bipolar spectrum disorder characterized by the occurrence of at least one manic episode, with or without mixed or psychotic features. [1] Most people also, at other times, have one or more depressive episodes. [2]
Causes: Family history, previous diagnosis of a mood disorder, trauma, stress or major life changes in the case of depression, physical illness or use of certain medications. Depression has been linked to major diseases such as cancer, diabetes, Parkinson's disease and heart disease, Brain structure and function in the case of bipolar disorder. [1]
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