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The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
Georgios Nikolaou Papanikolaou (or George Papanicolaou / ˌ p æ p ə ˈ n ɪ k ə l aʊ /; Greek: Γεώργιος Ν. Παπανικολάου [papanikoˈlau]; 13 May 1883 – 19 February 1962) was a Greek physician, zoologist and microscopist who was a pioneer in cytopathology and early cancer detection, and inventor of the pap smear for detection of cervical cancer.
Brushes used to collect samples for cytology. Liquid-based cytology is a method of preparing samples for examination in cytopathology.The sample is collected, normally by a small brush, in the same way as for a conventional smear test, but rather than the smear being transferred directly to a microscope slide, the sample is deposited into a small bottle of preservative liquid.
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[1] [2] [3] The Papanicolaou stain is one of the most widely used stains in cytology, [1] where it is used to aid pathologists in making a diagnosis. Although most notable for its use in the detection of cervical cancer in the Pap test or Pap smear, it is also used to stain non- gynecological specimen preparations from a variety of bodily ...
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Andromachi "Mary" Mavrogeni Papanikolaou [note 1] (1890-13 October 1982) was a Greek laboratory technician and the wife of Georgios Papanikolaou, the Greek pathologist who independently invented the pap test. For 21 years, Mary Papanikolaou volunteered to have her cervix sampled and smeared by her husband to help with his efforts to create the ...