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Roth's spots, also known as Litten spots or the Litten sign, [1] are non-specific red lesions with white or pale centres, seen on the retina of the eye and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV.
Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender. [2] Osler's nodes can also be seen in Systemic lupus erythematosus; Marantic endocarditis; Disseminated gonococcal infection; Distal to infected arterial ...
Brushfield spots are small, white or greyish/brown spots on the periphery of the iris in the human eye due to aggregation of connective tissue, a normal constituent of the iris stroma. The spots are named after the physician Thomas Brushfield , who first described them in his 1924 M.D. thesis.
Janeway lesions present as red, painless macules and papules on the palms and soles. [1]They are not common and are frequently indistinguishable from Osler's nodes.Rarely, they have been reported in cases of systemic lupus erythematosis (SLE), gonococcemia (disseminated gonorrhoea), haemolytic anaemia and typhoid fever.
Some rosacea treatments such as Soolantra, which contains topical ivermectin, can improve rosacea symptoms. The gut-skin connection Much research is centered on better understanding the connection ...
A major cause of Bitot's spots is vitamin A deficiency (VAD). [4] Rarely, pellagra due to deficiency of vitamin B 3 (niacin) may also cause Bitot's spots. [5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)
The skin and the lens have the same embryological origin and so can be affected by similar diseases. [24] Those with atopic dermatitis and eczema occasionally develop shield ulcer cataracts. [ citation needed ] Ichthyosis is an autosomal recessive disorder associated with cuneiform cataracts and nuclear sclerosis.
UPDATE, 8/20/24 at 11:55 a.m. ET: TikTok star Kyle Marisa Roth’s cause of death has been revealed four months after her April death. Roth’s death was caused by a cardiac arrhythmia due to ...