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  2. RNA polymerase I - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase_I

    RNA polymerase I. RNA polymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized by RNA polymerase III), a type of RNA that accounts for over 50% of the total RNA synthesized in a cell. [1]

  3. RNA polymerase - Wikipedia

    en.wikipedia.org/wiki/RNA_polymerase

    In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that catalyzes the chemical reactions that synthesize RNA from a DNA template. Using the enzyme helicase, RNAP locally opens the double-stranded DNA so that one strand of the exposed nucleotides can ...

  4. Eukaryotic transcription - Wikipedia

    en.wikipedia.org/wiki/Eukaryotic_transcription

    t. e. Eukaryotic Transcription. Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of transportable complementary RNA replica. [1] Gene transcription occurs in both eukaryotic and prokaryotic cells. Unlike prokaryotic RNA polymerase that initiates the transcription of ...

  5. RNA-dependent RNA polymerase - Wikipedia

    en.wikipedia.org/wiki/RNA-dependent_RNA_polymerase

    RNA-dependent RNA polymerase (RdRp) or RNA replicase is an enzyme that catalyzes the replication of RNA from an RNA template. Specifically, it catalyzes synthesis of the RNA strand complementary to a given RNA template. This is in contrast to typical DNA-dependent RNA polymerases, which all organisms use to catalyze the transcription of RNA ...

  6. Gene expression - Wikipedia

    en.wikipedia.org/wiki/Gene_expression

    Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype. These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA (snRNA ...

  7. Nucleolus - Wikipedia

    en.wikipedia.org/wiki/Nucleolus

    In ribosome biogenesis, two of the three eukaryotic RNA polymerases (Pol I and Pol III) are required, and these function in a coordinated manner. In an initial stage, the rRNA genes are transcribed as a single unit within the nucleolus by RNA polymerase I. In order for this transcription to occur, several pol I-associated factors and DNA ...

  8. Ribosome biogenesis - Wikipedia

    en.wikipedia.org/wiki/Ribosome_biogenesis

    Ribosome biogenesis is a very tightly regulated process, and it is closely linked to other cellular activities like growth and division. [3][4] Some have speculated that in the origin of life, ribosome biogenesis predates cells, and that genes and cells evolved to enhance the reproductive capacity of ribosomes. [5]

  9. Selective factor 1 - Wikipedia

    en.wikipedia.org/wiki/Selective_factor_1

    Selective factor 1. Role of transcription factor in gene expression regulation. Selective factor 1 (also known as SL1) is a transcription factor that binds to the promoter of genes and recruits a preinitiation complex to which RNA polymerase I will bind to and begin the transcription of ribosomal RNA (rRNA). [1][2]