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Since Pyrantel is poorly absorbed by the host's intestine, the host is unaffected by the small dosage of medication used. Spastic (tetanic) paralyzing agents, in particular pyrantel pamoate, may induce complete intestinal obstruction in a heavy worm load. [8]
Treatment is typically with two doses of the medications mebendazole, pyrantel pamoate, or albendazole two weeks apart. [4] Everyone who lives with or takes care of an infected person should be treated at the same time. [1] Washing personal items in hot water after each dose of medication is recommended. [1]
If used by itself it causes the worm to be passed out in the feces. Dosage is 75 mg/kg (max 3.5 g) as a single oral dose. [citation needed] Pyrantel pamoate (Antiminth, Pin-Rid, Pin-X), depolarizes ganglionic block of nicotinic neuromuscular transmission, resulting in spastic paralysis of the worm. Spastic (tetanic) paralyzing agents, in ...
Those recommended by the World Health Organization for ascariasis are: albendazole, mebendazole, levamisole and pyrantel pamoate. [2] Single-dose of albendazole, mebendazole, and ivermectin are effective against ascariasis. They are effective at removing parasites and eggs from the intestines. [35]
Drontal (combination with pyrantel pamoate) (Bayer) for veterinary use; D-Worm for veterinary use; note that D-Worm also makes roundworm medicine containing piperidine which is not effective against tapeworms. Fish Tapes (Thomas Labs) for aquarium use; Interceptor Plus chewable tablets (combination with milbemycin) for veterinary use. Note ...
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Pyrantel pamoate – effective against most parasitic nematodes of the GIT; Macrocyclic lactones are glutamate-gated chloride channel agonists, [8] and include: Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass ...
In the article, it says: "Dosage is 11 mg/kg not to exceed 1 g as a single dose." Does this mean 11mg of pyrantel embonate or 11mg of pure pyrantel? In the package insert of a German pyrantel drug ("Helmex"), it says dosage is 10mg/kg, with one tablet containing 720mg of pyrantel embonate equivalent to 250mg of pure pyrantel.