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This is an accepted version of this page This is the latest accepted revision, reviewed on 16 February 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
Normal cells typically generate only about 30% of energy from glycolysis, [118] whereas most cancers rely on glycolysis for energy production (Warburg effect). [ 119 ] [ 120 ] But a minority of cancer types rely on oxidative phosphorylation as the primary energy source, including lymphoma , leukemia , and endometrial cancer . [ 121 ]
DNA microarrays have compared normal cells to breast cancer cells and found differences in the expression of hundreds of genes. Although the significance of many of those genetic differences is unknown, independent analyses by different research groups has found that certain groups of genes have a tendency to co-express.
The Wnt signaling pathway normally plays an important role for normal function of these cells including maintaining this lining. Mutations can be inherited or acquired, and most probably occur in the intestinal crypt stem cell. [47] [48] [49] The most commonly mutated gene in all colorectal cancer is the APC gene, which produces the APC protein ...
Non-small-cell lung cancer (NSCLC), or non-small-cell lung carcinoma, is any type of epithelial lung cancer other than small-cell lung cancer (SCLC). NSCLC accounts for about 85% of all lung cancers.
19645 Ensembl ENSG00000139687 ENSMUSG00000022105 UniProt P06400 P13405 RefSeq (mRNA) NM_000321 NM_009029 RefSeq (protein) NP_000312 NP_000312.2 NP_033055 Location (UCSC) Chr 13: 48.3 – 48.6 Mb Chr 14: 73.42 – 73.56 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The retinoblastoma protein (protein name abbreviated Rb or pRb ; gene name abbreviated Rb, RB or RB1) is a tumor ...