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Any research in life sciences is proposed to answer a scientific question we might have. To answer this question with a high certainty, we need accurate results. The correct definition of the main hypothesis and the research plan will reduce errors while taking a decision in understanding a phenomenon.
The complexity of systems addressed by microscale models leads to complexity in the models themselves, and the specification of a microscale model can be tens or hundreds of times larger than its corresponding macroscale model. (The simplified example of Figure 2 has 25 times as many lines in its specification as does Figure 1.)
Figure 1. Example of a biological network between genes and proteins that controls entry into S phase. However, with knowledge of network interactions and a set of parameters for the proteins and protein interactions (usually obtained through empirical research), it is often possible to construct a model of the network as a dynamical system.
Onymacris unguicularis beetle with landmarks for morphometric analysis. In landmark-based geometric morphometrics, the spatial information missing from traditional morphometrics is contained in the data, because the data are coordinates of landmarks: discrete anatomical loci that are arguably homologous in all individuals in the analysis (i.e. they can be regarded as the "same" point in each ...
In any case, users of a model need to understand the assumptions made that are pertinent to its validity for a given use. Building a model requires abstraction. Assumptions are used in modelling in order to specify the domain of application of the model. For example, the special theory of relativity assumes an inertial frame of reference.
Allometry (Ancient Greek ἄλλος állos "other", μέτρον métron "measurement") is the study of the relationship of body size to shape, [1] anatomy, physiology and behaviour, [2] first outlined by Otto Snell in 1892, [3] by D'Arcy Thompson in 1917 in On Growth and Form [4] and by Julian Huxley in 1932.
A variety of objective means exist to empirically measure biodiversity. Each measure relates to a particular use of the data, and is likely to be associated with the variety of genes. Biodiversity is commonly measured in terms of taxonomic richness of a geographic area over a time interval. In order to calculate biodiversity, species evenness ...
Mathematical and theoretical biology, or biomathematics, is a branch of biology which employs theoretical analysis, mathematical models and abstractions of living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of ...