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This therapy ties to the Hygiene hypothesis in that the lack of exposure to bacteria and parasites such as helminths can cause a weaker immune system leading to being more susceptible to autoimmune disease. [4] [5] Helminth worms are members of two phyla: nematodes, which are primarily used in human helminthic therapy, and flat worms . [2]
The soil-transmitted helminths (A. lumbricoides, T. trichiura, N. americanus, A. duodenale), schistosomes, and filarial worms collectively infect more than a quarter of the human population worldwide at any one time, far surpassing HIV and malaria together. [35] [37] Schistosomiasis is the second most prevalent parasitic disease of humans after ...
The effects of parasitic worms, or helminths, on the immune system is a recently emerging topic of study among immunologists and other biologists. Experiments have involved a wide range of parasites, diseases, and hosts. The effects on humans have been of special interest.
First-hand experiences with the parasites posted on Helminthic Therapy Forum, a Yahoo! chat group, show that those who've benefited from the treatment feel the risks are well worth it. "My ...
Hookworms attached to the intestinal mucosa Two pinworms Image showing life cycle inside and outside of the human body of one fairly typical and well described helminth: Ascaris lumbricoides. Helminths are a group of organisms which share a similar form but are not necessarily evolutionarily related. The term "helminth" is an artificial term.
Helminthic therapy is the treatment of autoimmune diseases and immune disorders by means of deliberate infestation with a helminth larva or ova. Helminthic therapy emerged from the search for reasons why the incidence of immunological disorders and autoimmune diseases correlates with the level of industrial development.