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  2. Recreational use of dextromethorphan - Wikipedia

    en.wikipedia.org/wiki/Recreational_use_of_dext...

    William E. White, author of the "DXM FAQ", has compiled informal research from correspondence with dextromethorphan users suggesting that heavy abuse may result in various deficits corresponding to the brain areas affected by Olney's lesions; these include loss of episodic memory, decline in ability to learn, abnormalities in some aspects of ...

  3. Anti-obesity medication - Wikipedia

    en.wikipedia.org/wiki/Anti-obesity_medication

    Weight loss drugs have been developed since the early twentieth century, and many have been banned or withdrawn from the market due to adverse effects, including deaths; other drugs proved ineffective. Although many earlier drugs were stimulants such as amphetamines, in the early 2020s, GLP-1 receptor agonists became popular for weight loss.

  4. 9 Negatives of Drinking Soda (Plus 4 Healthier Alternatives)

    www.aol.com/9-negatives-drinking-soda-plus...

    If you’re working towards weight loss goals, soda isn’t your friend. It’s high in added sugar — often upwards of 40 grams per can — mostly in the form of high fructose corn syrup.

  5. Synthetic cannabinoids - Wikipedia

    en.wikipedia.org/wiki/Synthetic_cannabinoids

    These are achieved at lower doses, because many synthetic cannabinoids are more potent than marijuana, and users are often unaware of exactly what they are getting and how potent it is. [62] For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8]

  6. US FDA flags dosing risks from compounded versions of ... - AOL

    www.aol.com/news/us-fda-flags-dosing-risks...

    (Reuters) -The U.S. Food and Drug Administration on Friday warned patients and doctors about dosing errors associated with compounded versions of Novo Nordisk's weight-loss and diabetes drugs.

  7. Tetrahydrocannabivarin - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrocannabivarin

    THCV is an antagonist of THC at CB 1 receptors and lessens the psychoactive effects of THC. [ 8 ] THCV also acts as an agonist of GPR55 and l-α-lysophosphatidylinositol (LPI), and beyond the endocannabinoid system , THCV also activate 5-HT1A receptors to produce an antipsychotic effect, that has shown therapeutic potential for ameliorating ...

  8. These 4 Factors Can Impact How Many Pounds You'll Lose ... - AOL

    www.aol.com/4-factors-impact-many-pounds...

    Basically, the kind of medication prescribed and dosage affected the weight loss outcome. Semaglutide resulted in more than double the average weight loss of liraglutide (5.1% versus 2.2%).

  9. 11-Hydroxy-THC - Wikipedia

    en.wikipedia.org/wiki/11-Hydroxy-THC

    Like Δ 9-THC, 11-hydroxy-THC is a partial agonist at the cannabinoid receptor CB 1, but with significantly higher binding affinity (K i = 0.37 nM compared to Δ 9-THC K i = 35 nM). [7] With respect to cAMP inhibition at CB 1 it displays a similar efficacy to that of Δ 9 -THC (EC 50 = 11 nM vs. EC 50 = 5.2 nM, respectively), but a lower ...