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drug sensitization or reverse tolerance – the escalating effect of a drug resulting from repeated administration at a given dose. drug withdrawal – symptoms that occur upon cessation of repeated drug use. physical dependence – dependence that involves persistent physical– somatic withdrawal symptoms (e.g., fatigue and delirium tremens)
Opioid withdrawal is a set of symptoms (a syndrome) arising from the sudden cessation or reduction of opioids where previous usage has been heavy and prolonged. [1][2] Signs and symptoms of withdrawal can include drug craving, anxiety, restless legs syndrome, nausea, vomiting, diarrhea, sweating, and an elevated heart rate.
A study into the effects of the benzodiazepine receptor antagonist, flumazenil, on benzodiazepine withdrawal symptoms persisting after withdrawal was carried out by Lader and Morton. Study subjects had been benzodiazepine-free for between one month and five years, but all reported persisting withdrawal effects to varying degrees.
Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...
As the chart below shows, traces of drugs like LSD, morphine, heroin, amphetamines, and alcohol all remain in the blood for just 12 hours or less: bi_graphics_how long drugs stay in your blood ...
Symptoms. Effects of long-term benzodiazepine use may include disinhibition, impaired concentration and memory, depression, [19][20] as well as sexual dysfunction. [6][21] The long-term effects of benzodiazepines may differ from the adverse effects seen after acute administration of benzodiazepines. [22] An analysis of cancer patients found ...
tolerance – the diminishing effect of a drug resulting from repeated administration at a given dose. v. t. e. Physical dependence is a physical condition caused by chronic use of a tolerance -forming drug, in which abrupt or gradual drug withdrawal causes unpleasant physical symptoms. [4][5] Physical dependence can develop from low-dose ...
Benzodiazepine dependence (BZD dependence) defines a situation in which one has developed one or more of either tolerance, withdrawal symptoms, drug seeking behaviors, such as continued use despite harmful effects, and maladaptive pattern of substance use, according to the DSM-IV. In the case of benzodiazepine dependence, the continued use ...