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Equianalgesic. An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1] Tables of this general type are also available for ...
Oral hydrocodone has a mean equivalent daily dosage (MEDD) factor of 0.4, meaning that 1 mg of hydrocodone is equivalent to 0.4 mg of intravenous morphine. However, because of morphine's low oral bioavailability , there is a 1:1 correspondence between orally administered morphine and orally administered hydrocodone.
Hydrocodone diversion and recreational use has escalated due to its opioid effects. [12] In 2009 and 2010, hydrocodone was the second most frequently encountered opioid in the pharmaceutical industry.
Hydrocodone/ibuprofen (INNs), sold under the brand name Vicoprofen, is a fixed-dose combination analgesic medication used in short-term therapy to relieve severe pain. [3][4] Vicoprofen combines the analgesic and antitussive properties of hydrocodone with the analgesic, anti-inflammatory, and antipyretic properties of ibuprofen. [1]
One size fits all — A general rule of thumb is that the first year of a dog's life is equivalent to 15 human years, the second year equivalent to 9 human years, and each subsequent year about 5 human years. [3] So, a dog age 2 is equivalent to a human age 24, while a dog age 10 is equivalent to a human age 64.
Opioids are a class of drugs that derive from, or mimic, natural substances found in the opium poppy plant. Opioids work in the brain to produce a variety of effects, including pain relief. As a class of substances, they act on opioid receptors to produce morphine -like effects. [2][3]
Norhydrocodone. Norhydrocodone is the major metabolite of the opioid analgesic hydrocodone. [1] It is formed from hydrocodone in the liver via N- demethylation predominantly by CYP3A4. [1] Unlike hydromorphone, a minor metabolite of hydrocodone, norhydrocodone is described as inactive. [2] However, norhydrocodone is actually an agonist of the ...
Benzhydrocodone (contracted from benzoate-hydrocodone) is an opioid prodrug of the morphinan class. Its chemical structure consists of hydrocodone coupled with benzoic acid . Benzhydrocodone itself is inactive and acts as a prodrug to hydrocodone upon cleavage of the benzoate portion of the molecule.