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Malaria prophylaxis is the preventive treatment of malaria. Several malaria vaccines are under development. For pregnant women who are living in malaria endemic areas, routine malaria chemoprevention is recommended. It improves anemia and parasite level in the blood for the pregnant women and the birthweight in their infants. [1]
Prevention of malaria may be more cost-effective than treatment of the disease in the long run, but the initial costs required are out of reach of many of the world's poorest people. There is a wide difference in the costs of control (i.e. maintenance of low endemicity) and elimination programs between countries.
Malaria vaccines are vaccines that prevent malaria, a mosquito-borne infectious disease which affected an estimated 249 million people globally in 85 malaria-endemic countries and areas and caused 608,000 deaths in 2022. [2] The first approved vaccine for malaria is RTS,S, known by the brand name Mosquirix. [1]
The history of malaria extends from its prehistoric origin as a zoonotic disease in the primates of Africa through to the 21st century. A widespread and potentially lethal human infectious disease, at its peak malaria infested every continent except Antarctica . [ 1 ]
The recommendation applies only for areas with high malaria transmission and low resistance against SP, both measures are not free of controversy and only available for few spots in Africa. With the recent drop of malaria transmission in wide stretches of Africa [30] [31] and a steady increase in SP resistance [32] [33] few malaria control ...
Global malaria efforts, including those of PMI, have cut malaria mortality by over 60%, saved nearly 7 million lives, and prevented more than 1 billion malaria cases between 2000 and 2015. [5] PMI currently supports malaria prevention and control for over 500 million at-risk people in Africa. [3]
The disease was first linked to malaria by the Sierra Leone Creole physician John Farrell Easmon in his 1884 pamphlet entitled The Nature and Treatment of Blackwater Fever. Easmon coined the name "blackwater fever" and was the first to successfully treat such cases following the publication of his pamphlet.
The prevention of malaria through the use of LLINs is a key strategy for rolling back malaria in Africa. According to model-generated estimates based on the number of LLINs supplied by the manufacturers, the number distributed by national malaria control programmes and data from household surveys, the percentage of households with at least one ...