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Hydrogen therapy is the use of molecular hydrogen (H 2) for therapeutic purposes. H 2 has therapeutic benefits due to its antioxidant and anti-inflammatory effects, as well as due to its role as an inducer of gene expression , [ 1 ] H 2 is not cytotoxic or explosive below 4% concentration. [ 2 ]
In a certain rat model of Parkinson's disease, the brain's hydrogen sulfide concentration was found to be reduced, and administering hydrogen sulfide alleviated the condition. [14] In trisomy 21 (Down syndrome) the body produces an excess of hydrogen sulfide. [3] Hydrogen sulfide is also involved in the disease process of type 1 diabetes.
The tears are unique among body fluids in that they are exposed to the environment. Much like other body fluids, tear fluid is kept in a tight pH range using the bicarbonate buffer system. [ 15 ] The pH of tears shift throughout a waking day, rising "about 0.013 pH units/hour" until a prolonged closed-eye period causes the pH to fall again. [ 15 ]
Pressure ulcers can trigger other ailments, cause considerable suffering, and can be expensive to treat. Some complications include autonomic dysreflexia, bladder distension, bone infection, pyarthrosis, sepsis, amyloidosis, anemia, urethral fistula, gangrene and very rarely malignant transformation (Marjolin's ulcer – secondary carcinomas in chronic wounds).
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
Hydrogen, as atomic H, is the most abundant chemical element in the universe, making up 75% of normal matter by mass and >90% by number of atoms. [101] In astrophysics, neutral hydrogen in the interstellar medium is called H I and ionized hydrogen is called H II. [102] Radiation from stars ionizes H I to H II, creating spheres of ionized H II ...
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