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The characteristics are typical of demyelinating neuropathy with antimyelin-associated glycoprotein (MAG) antibodies; however, anti-MAG neuropathy is not included in the CIDP criteria according to the EFNS/PNS criteria, primarily due to the presence of a particular antibody and a different response to treatment.
Other concerns of neural tissue engineering include establishing safe sources of stem cells and getting reproducible results from treatment to treatment. [16] Alternatively, these stem cells can act as carriers for other therapies, though the positive effects of using stem cells as a delivery mechanism has not been confirmed.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Treatments include intravenous immunoglobulin, which is a short-term treatment, immunosuppressants, though they have not been shown to be effective, autologous stem cell transplantation, and rituximab. [1] [2] [3]
Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.
Eva Lucille Feldman is an American physician-scientist known for her work in the field of neurodegenerative diseases.She serves as the Russell N. DeJong Professor of Neurology at the University of Michigan, as well as the Director of the NeuroNetwork for Emerging Therapies and ALS Center of Excellence at Michigan Medicine.
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