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In enzymology, a glycerol-3-phosphate oxidase (EC 1.1.3.21) is an enzyme that catalyzes the chemical reaction. sn-glycerol 3-phosphate + O 2 glycerone phosphate + H 2 O 2. Thus, the two substrates of this enzyme are sn-glycerol 3-phosphate and O 2, whereas its two products are dihydroxyacetone phosphate (DHAP) and H 2 O 2.
Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (a.k.a. glycerone phosphate, outdated) to sn-glycerol 3-phosphate. [2] Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism.
Glycerol 3-phosphate is synthesized by reducing dihydroxyacetone phosphate (DHAP), an intermediate in glycolysis. The reduction is catalyzed by glycerol-3-phosphate dehydrogenase. DHAP and thus glycerol 3-phosphate can also be synthesized from amino acids and citric acid cycle intermediates via the glyceroneogenesis pathway. + NAD(P)H + H + → ...
The 3 substrates of this enzyme are sn-glycerol 3-phosphate, NAD +, and NADP +, whereas its 4 products are glycerone phosphate, NADH, NADPH, and H +. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. The systematic name of this enzyme class is sn ...
Thus, the two substrates of this enzyme are sn-glycerol 3-phosphate and D-glucose, whereas its two products are glycerol and D-glucose 6-phosphate. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this ...
In enzymology, a NADH peroxidase (EC 1.11.1.1) is an enzyme that catalyzes the chemical reaction. NADH + H + + H 2 O 2 NAD + + 2 H 2 O. The presumed function of NADH peroxidase is to inactivate H 2 O 2 generated within the cell, for example by glycerol-3-phosphate oxidase during glycerol metabolism or dismutation of superoxide, before the H 2 O 2 causes damage to essential cellular components.
Identifiers; EC no. 1.1.5.3: CAS no. 9001-49-4 : Alt. names: valpha-glycerophosphate dehydrogenase, alpha-glycerophosphate dehydrogenase (acceptor), anaerobic glycerol-3-phosphate dehydrogenase, DL-glycerol 3-phosphate oxidase (misleading), FAD-dependent glycerol-3-phosphate dehydrogenase, FAD-dependent sn-glycerol-3-phosphate dehydrogenase, FAD-GPDH, FAD-linked glycerol 3-phosphate ...
Triglycerides are built from three fatty acids, esterified onto each of three hydroxy groups of glycerol, which is derived from glycerol 3-phosphate.In mammals, glycerol 3-phosphate is usually synthesized through glycolysis, a metabolic pathway that degrades glucose into fructose 1,6-bisphosphate and then into two molecules of dihydroxyacetone phosphate, which beget glycerol 3-phosphate and ...